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Inhibit-E – 90 caps

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  • Helps Lower Estrogen AND Promotes  Healthy Estrogen Regulation & Metabolism*
  • Maximize Natural Testosterone Production*
  • Promote Hard, Lean, Dry Muscle Gains*
  • Promote Enhanced Body Composition*
  • Shed Excess Fluid Weight*

High Affinity AI/Anti-Estrogen – Helps Promote Healthy Estrogen Regulation & Metabolism* 

Potent Hormone Modulator for a Harder, Dryer, Leaner Physique*

Inhibit-E contains a precision blended combination of cutting edge, unique nutraceutical compounds that not only lower estrogen, but may also help promote healthy estrogen regulation and metabolism while boosting natural testosterone levels.

Battling estrogen can be a heck of a battle. You bust your butt in the gym, watch what you eat, but you just can’t get the results that you want; the results that you DESERVE. Estrogen can cause your body to store fat, make you feel bloated, and counteract all your efforts. It can also make you feel sluggish and negatively impact your testosterone levels.

Inhibit-E Highlights
  • Helps Lower Estrogen AND Promotes Healthy Estrogen Regulation & Metabolism*
  • Maximize Natural Testosterone Production*
  • Promote Hard, Lean, Dry Muscle Gains*
  • Promote Enhanced Body Composition*
  • Shed Excess Fluid Weight*
  • Do you want a leaner, dryer, more attractive physique?
  • Do you feel bloated?
  • Is icky water weight covering up the body you have worked so hard to get?
  • Are you trying to get in the best shape of your life?
  • Are you storing fat no matter how hard you are trying to lose it?
  • Are you storing fat but aren’t sure why?
  • Are you busting your butt in the gym but still aren’t getting the results you want, the results that you DESERVE?
  • Do you want a supplement that works as hard for you as you do?
  • Are you on or coming off of an anabolic cycle where an AI/Anti-Estrogen is needed?
  • Have you done anabolic cycles in the past and are still experiencing estrogen issues?
  • If you answered yes to any of the above questions, Inhibit-E may be right for you.

  • References

  • Balunas MJ, Su B, Riswan S, Fong HH, Brueggemeier RW, Pezzuto JM, Kinghorn AD. Isolation and Characterization of Aromatase Inhibitors from Brassaiopsis glomerulata (Araliaceae). Phytochem Lett. 2009 Feb 19;2(1):29-33.
  • Wu, W.-T. (2012). Evaluation of anti-inflammatory effects of Broussonetia papyrifera stem bark. Indian Journal of Pharmacology.
  • * These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

  • Zhou, X.-J., Mei, R.-Q., Zhang, L., Lu, Q., Zhao, J., Adebayo, A. H., & Cheng, Y.-X. (2010). Antioxidant phenolics from Broussonetia papyrifera fruits. Journal of Asian natural products research, 12(5), 399-406.
  • Balunas, M. J., Su, B., Brueggemeier, R. W., & Kinghorn, A. D. (2008). Natural products as aromatase inhibitors. Anti-cancer agents in medicinal chemistry, 8(6), 646-682.
  • De Bock, M.; Derraik, J. G. B.; Brennan, C. M.; Biggs, J. B.; Morgan, P. E.; Hodgkinson, S. C.; Hofman, P. L.; Cutfield, W. S. (2013). “Olive (Olea europaea L.) Leaf Polyphenols Improve Insulin Sensitivity in Middle-Aged Overweight Men: A Randomized, Placebo-Controlled, Crossover Trial”. In Nerurkar, Pratibha V. PLoS ONE 8 (3): e57622.
  • Sudjana, Aurelia N.; D’Orazio, Carla; Ryan, Vanessa; Rasool, Nooshin; Ng, Justin; Islam, Nabilah; Riley, Thomas V.; Hammer, Katherine A. (2009). “Antimicrobial activity of commercial Olea europaea (olive) leaf extract”. International Journal of Antimicrobial Agents 33 (5): 461–3. doi:10.1016/j.ijantimicag.2008.10.026. PMID 19135874.
  • Oi-Kano, Yuriko; Kawada, Teruo; Watanabe, Tatsuo; Koyama, Fumihiro; Watanabe, Kenichi; Senbongi, Reijirou; Iwai, Kazuo (2008). “Oleuropein, a Phenolic Compound in Extra Virgin Olive Oil, Increases Uncoupling Protein 1 Content in Brown Adipose Tissue and Enhances Noradrenaline and Adrenaline Secretions in Rats”. Journal of Nutritional Science and Vitaminology 54 (5): 363–70.
  • Haris Omar, Syed (2010). “Oleuropein in Olive and its Pharmacological Effects”. Scientia Pharmaceutica 78 (2): 133–54. doi:10.3797/scipharm.0912-18.
  • de Bock M, Thorstensen EB, Derraik JG, Henderson HV, Hofman PL, Cutfield WS (2013) Human absorption and metabolism of oleuropein and hydroxytyrosol ingested as olive (Olea europaea L.) leaf extract. Mol Nutr Food Res.
  • Dashwood, Rod H.; Arbogast, D.N.; Fong, A.T.; Pereira, C.; Hendricks, J.D.; Bailey, G.S. (1989). “Quantitative inter-relationships between aflatoxin B1 carcinogen dose, indole-3-carbinol anti-carcinogen dose, target organ DNA adduction and final tumor response”. Carcinogenesis 10 (1): 175–81. doi:10.1093/carcin/10.1.175. PMID 2491968.
  • Hsu, J; Dev, A; Wing, A; Brew, C; Bjeldanes, L; Firestone, G (2006). “Indole-3-carbinol mediated cell cycle arrest of LNCaP human prostate cancer cells requires the induced production of activated p53 tumor suppressor protein”. Biochemical Pharmacology 72 (12): 1714–23.
  • Auborn, K. J., Fan, S., Rosen, E. M., Goodwin, L., Chandraskaren, A., Williams, D. E., Chen, D., et al. (2003). Indole-3-carbinol is a negative regulator of estrogen. The Journal of nutrition, 133(7 Suppl), 2470S-2475S.
  • Grubbs, C. J., Steele, V. E., Casebolt, T., Juliana, M. M., Eto, I., Whitaker, L. M., Dragnev, K. H., et al. (1995). Chemoprevention of chemically-induced mammary carcinogenesis by indole- 3-carbinol. Anticancer Res, 15(3), 709-716.
  • Brignall, M. S. (2001). Prevention and treatment of cancer with indole-3-carbinol. Alternative medicine review : a journal of clinical therapeutic, 6(6), 580-589.
  • Park, M.-K., Rhee, Y.-H., Lee, H.-J., Lee, E.-O., Kim, K.-H., Park, M.-J., Jeon, B.-H., et al. (2008). Antiplatelet and antithrombotic activity of indole-3-carbinol in vitro and in vivo. Phytotherapy research : PTR, 22(1), 58-64.
  • Sarkar, F. H., & Li, Y. (2004). Indole-3-carbinol and prostate cancer. The Journal of nutrition, 134(12 Suppl), 3493S-3498S.
  • Nachshon-Kedmi, M., Yannai, S., Haj, A., & Fares, F. A. (2003). Indole-3-carbinol and 3,3ʼ-diindolylmethane induce apoptosis in human prostate cancer cells. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 41(6), 745-752.
  • Garikapaty, V. P. S., Ashok, B. T., Chen, Y. G., Mittelman, A., Iatropoulos, M., & Tiwari, R. K. (2005). Anti-carcinogenic and anti-metastatic properties of indole-3-carbinol in prostate cancer. Oncology reports, 13(1), 89-93.
  • Hirata A, Murakami Y, Shoji M, Kadoma Y, Fujisawa S (2005). “Kinetics of radical-scavenging activity of hesperetin and hesperidin and their inhibitory activity on COX-2 expression”. Anticancer Res. 25 (5): 3367–74. PMID 16101151.
  • Monforte MT, Trovato A, Kirjavainen S, Forestieri AM, Galati EM, Lo Curto RB (September 1995). “Biological effects of hesperidin, a Citrus flavonoid. (note II): hypolipidemic activity on experimental hypercholesterolemia in rat”. Farmaco 50 (9): 595–9. PMID 7495469.
  • Ohtsuki K, Abe A, Mitsuzumi H, et al. (December 2003). “Glucosyl hesperidin improves serum cholesterol composition and inhibits hypertrophy in vasculature”. J. Nutr. Sci. Vitaminol. 49 (6): 447–50. PMID 14974738.
  • Chiba H, Uehara M, Wu J, et al. (June 2003). “Hesperidin, a citrus flavonoid, inhibits bone loss and decreases serum and hepatic lipids in ovariectomized mice”. J. Nutr. 133 (6): 1892–7. PMID 12771335.
  • Kawaguchi K, Kikuchi S, Hasunuma R, Maruyama H, Yoshikawa T, Kumazawa Y (May 2004). “A citrus flavonoid hesperidin suppresses infection-induced endotoxin shock in mice”. Biol. Pharm. Bull. 27 (5): 679–83. doi:10.1248/bpb.27.679. PMID 15133244.
  • Emim JA, Oliveira AB, Lapa AJ (February 1994). “Pharmacological evaluation of the anti-inflammatory activity of a citrus bioflavonoid, hesperidin, and the isoflavonoids, duartin and claussequinone, in rats and mice”. J. Pharm. Pharmacol. 46 (2): 118–22. PMID 8021799.
  • Galati EM, Monforte MT, Kirjavainen S, Forestieri AM, Trovato A, Tripodo MM (November 1994). “Biological effects of hesperidin, a citrus flavonoid. (Note I): antiinflammatory and analgesic activity”. Farmaco 40 (11): 709–12. PMID 7832973.
  • Loscalzo LM, Wasowski C, Paladini AC, Marder M (February 2008). “Opioid receptors are involved in the sedative and antinociceptive effects of hesperidin as well as in its potentiation with benzodiazepines”. Eur. J. Pharmacol. 580 (3): 306–13. doi:10.1016/j.ejphar.2007.11.011. PMID 18048026.
  • Guzmán-Gutiérrez SL, Navarrete A (March 2009). “Pharmacological exploration of the sedative mechanism of hesperidin identified as the active principle of Citrus sinensis flowers”. Planta Med. 75 (4): 295–301. doi:10.1055/s-0029-1185306. PMID 19219759.
  • Al-Ashaal HA, El-Sheltawy ST”Antioxidant capacity of hesperidin from citrus peel using electron spin resonance and cytotoxic activity against human carcinoma cell lines. Pharm Biol. 2011 Mar;49(3):276-82
  • Chan, F. L., Chen, S., Ye, L., & Leung, L. K. (2012). The citrus flavonone hesperetin inhibits growth of aromatase-expressing MCF-7 tumor in ovariectomized athymic mice. The Journal of Nutritional Biochemistry.
  • Li, F., Ye, L., Lin, S.-M., & Leung, L. K. (2011). Dietary flavones and flavonones display differential effects on aromatase (CYP19) transcription in the breast cancer cells MCF-7. Molecular and cellular endocrinology, 344(1-2), 51-58.
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